domingo, 22 de novembro de 2015

Researcher believes that substance developed at USP cure cancer

'The fosfoamina is there, available to anyone who wants to cure cancer, "he says.
Patients went to court to obtain capsules in São Carlos, Brazil.

A retired professor at the University of São Paulo (USP) believes that managed to develop a substance that can cure cancer. Gilberto Orivaldo Chierice coordinated for more than 20 years studies with synthetic phosphoethanolamine that mimics a substance present in the body and signals for removing cancer cells by the immune system. "The fosfoamina is there, available to anyone who wants to cure cancer," said the expert.
As shown by G1, the drug was provided free in San Carlos, but a university ordinance prohibited the distribution to the registration with the National Health Surveillance Agency (Anvisa) and patients who were aware of studies went to court to get the capsules. When contacted, Anvisa said it did not identify a formal process for evaluating the product in their records and that there was by the research institution no practical initiative or attitude towards transforming the product into a drug. According to the agency, for the record, in addition to the request, it needs to present documents and medical tests.
But, according to Chierice the substance, also known as fosfoamina not hit the market for "ill will" of the authorities. He said he sought Anvisa four times and was reported missing clinical data. "That is the claim of everyone. But it's full of drugs in this country who do not have clinical data," he declared.
He then asked the agency to a public hospital where he could carry out further tests - the researchers say, in the 90s, the substance was tested at a hospital in Jau - but said he did not get back. Anvisa denies he was formally sought.
Action
The retired teacher explained that with the intake of the capsules, the cancer cells are killed and the tumor disappears between six and eight months of treatment. "But it is evident that a case is different from the other," he said, stressing that the period may vary according to each immune system.
It also counted as the substance reacts and says there is already another country interested in manufacturing it. "We may have to buy that product the international market cost because it is already beginning to bore stay all this time trying to not get" fired in the interview granted to the reporter Rafael Castro and reproduced below.
EPTV - What substance is this?
It is the combination of a very common substance used in many hair shampoos, called monoethanolamine, and phosphoric acid, which is a food preservative. The combination of these two compounds produces a substance called phosphoethanolamine, which is a marker of differentiated cells, which are considered cancer cells.
EPTV - As it acts in the body?
This substance ourselves manufacture within the long muscle cells and liver endoplasmic reticulum. So we can not call it natural product because it is synthesized, but your body already makes for the same purpose: to defend you at all times of your life cells that differentiate.
EPTV - In practice, this substance reinforces what we already have? How it acts in the cancer cell?
First, it passes the digestive tract to the bloodstream, it goes to the liver and forms a reaction with the fatty acid. What is this fatty acid? It is the substance that is fed to the tumor. It tumor energy. And it goes along with this substance inside the cell. When she comes in, that cell is relatively still, ie the main organelle her, called mitochondria, is stopped. It forces the mitochondria to work and when it forces, it denounces to the immune system and the cell is settled, is called apoptosis (see the process in the video below).
EPTV - The efficacy of the substance was more evident on some kind of tumor?
Tumors have cells similar in its mechanism anaerobic calls. Anaerobic tumor cells, all of them yielded by the action of fosfoamina.
EPTV - There was a type of tumor efficacy has greater?
It can not make this measure because, first, we are not doctors. I would have to have a partnership with the doctor for him to show the effectiveness of each. This has never been done.
EPTV - Is there any contraindications? The capsule has to be ingested before the person to do chemotherapy?
There is no "before" because it does not work as an adjunct. If you blow the immune system of the person, the results are not good because the action of fosfoamina requires that the immune system is intact. If there is no chemotherapy which destroys the immune system, perfect, may be combined.
EPTV - You have an idea of ​​how many people have benefited from this substance in the last 20 years?
Lately we made about 50,000 capsules per month. This equates to 60 each person, 800 people or close to a thousand people a month. Now how many people have benefited I am not able to say because many of them, who were terminally ill, are there, alive. So I can not say how many people were healed.
EPTV - You published this study in several scientific journals. How many in total?
Today I suppose there are nine to ten work in the best oncology journals in the world, which are international journals, along with the staff of the [Institute] Butantan, and explain the fosfoamina mechanism of action.
EPTV - There was interest from another country that formula. What can hapen?
We may have to buy this drug at cost international market because it is already beginning to bore stay all this time trying and you can not create difficulties I can not explain. I am a 25 year old man of science, I'm no amateur, and not be amateur, I know the procedures of things, how it works. If it is not possible here, the best thing is another country to benefit people because it is no flag. Humanity needs someone to do something to cure their ills.
EPTV - A cure for cancer exists?
Not only for fosfoamina, there must be about a dozen other things, but fosfoamina is there, available to anyone who wants to cure cancer.
EPTV - And why the approval is taking so long? Why Anvisa's taking so long to release?
The reason is very simple: I think there is an unwillingness. Because, if there was goodwill, it had already been applied in government hospitals, as experimental data, phase I, phase II, phase III, all is ready. Now what is lacking is within law standards, clinical data, so I'm told atAnvisa all this time. I think there is an unwillingness.
EPTV - And while this "ill will" continue, many people with the disease, and the cure is closer than most people think, is not it?
Yeah, I think so. Healing is much closer. And if you still say that lack enhance something would have to be improved going forward, not going back. Going back're all set.
EPTV - This substance is a cure for cancer?
I believe so, I believe so. Not only this as a lot of them that could come from derivatives.
Understand the case
On the 17th, the G1 showed that cancer patients fight in court to the USP provide synthetic phosphoethanolamine capsules. According to users, relatives and lawyers, the medicinal accumulate satisfactory results in combating disease, including healing reports, but has no record at Anvisa and therefore is only being delivered by court order.
The drug, whose capsule is produced for less than R $ 0.10, led to the emergence of discussions on the internet and a resident of Santa Catarina that distributed free was arrested. In an interview with G1, Charles Kennedy Witthoeft said it was "with consciousness alone."
During a visit to São Carlos (SP), he told how he met the substance, pointed to by researchers as an alternative treatment for cancer, why would donate it and what happened after being arrested and charged with drug counterfeiting. "There's no way to measure what we felt every person who came to speak he was cured," he said.

Attacks in Paris: What are the consequences for Europe?

Attacks in France creates fear and mistrust among Europeans, who charge more concrete actions for security on the continent.
Taking the train on the night of Friday from Paris to Brussels, I had a bad feeling ─ as well as people who had boarded with me.
I could see the nervousness in their eyes as they sought their seats and at the same time, looked sideways shy and suspicious manner. How could we know who could there be suspicious?
Those who sought to spread fear and mistrust, undermining the security and stability of Europe ─ that, in general, we take for granted - got what they wanted.
Since that happened the attacks in Paris ─ all in common places, we attend on a daily basis ─ in a restaurant, on a show and close to a football stadium, there is a feeling of "vulnerability" in Europe: between parents with small children in crowded buses, between couples in love going to the movies.
Roma are installing metal detectors at the Coliseum after the FBI warned the city that Italian monuments could be "targets of terrorism."
Brussels has canceled an annual festival of students in the city center because of security concerns. On Saturday, the Belgian capital raised the terror alert to the maximum level.
The Copenhagen Airport had one of its terminals closed after a warning about a "suspicious package".
Sweden raised the national alert after receiving information about a planned attack ─ same reason the friendly between Germany and the Netherlands was canceled hastily in Hannover midweek.
There are armed guards and soldiers on the subway train stations.
There are military operations going on in residential areas in Paris and Brussels, and the search for gunmen and other suspects linked to attacks in the French capital continues.
The persons accompanying news are used to seeing this kind of disturbing image in the Middle East. But now they fear the chaos and bloodshed has come "at the doorstep".
United against the "EI"?
French President Francois Hollande, who usually does not usually talk much, already proclaimed a "war" against the group calling itself "Islamic state" this week.
Agree with him or not, these words have enormous consequences ─ for the French foreign policy in the Middle East, for civil liberties in France and for Europe as a whole.
The public outrage that engulfed the world after the attacks in Paris united European countries (at least superficially) ─ after a period of disagreements over the flow of immigrants and the euro crisis.
And the attacks in Paris can also "catalyze" a movement to bring Russia closer again.
France declared that wants to destroy the "EI" after the extremist group has taken over the authorship of the attacks in the French capital. But France can not do it alone. Russia is the leading candidate to help her in this task ─ and Moscow wants to seize the moment to end the sanctions imposed on the country after the annexation of the Crimea Peninsula.
The recent G20 meeting in Turkey had scenes that would be considered unlikely until then: the Russian President Vladimir Putin, speaking to the US president, Barack Obama, and the UK Prime Minister David Cameron.
It is still early to talk about a great "anti-coalition EI", but there are rumors that it may come soon.
Schengen Agreement
The timing is also critical for security issues in Europe.
The French Interior Minister, Bernard Cazeneuve, rebuked his fellow ministers for having "long lost" in the fight against terrorism and called for concrete actions.
Now the debate is being directed to the Schengen Agreement, signed in 1997, which sealed the free movement of people in 26 countries of the European Union.
The agreement is considered one of the greatest achievements of the European Union, but now has been criticized because it also ended up allowing the free movement of terrorists ─ one of the mentors of the attacks, for example, Abdelhamid Abaaoud, born in Belgium, traveled from Syria to the France without being identified.
France is now asking for a more effective use of the Schengen Information System, a database that would allow the security forces do alerts about individuals, objects and vehicles.
The country also wants to facilitate passenger information sharing traveling by plane and supports the creation of a genuine European agency to police the external borders ─ something that some ministers have objected.
Promises
The political promises tend to multiply after atrocities like those perpetrated in Paris, but a British security adviser told me that the secret services like to keep their information as well, secret.
Unfortunately, Europe has been the target of several terrorist attacks recently.
After Madrid in 2004 and London in 2005 and the attack on French satirical weekly Charlie Hebdo, promises were made of a "cooperation across borders."
But it eventually became, in effect, a "dispute between the borders."
Perhaps now occur differently.
There is a sense of greater urgency, with a growing prospect of further attacks.
The followers of Le Pen in France, the Wilders fans in the Netherlands, and of the Salvini in Italy want Europe to create a bridge with immigrants, but attacks in Paris raised the jihadist problem growing indoors.
The attacks on innocents in Paris are having a huge impact on Europe as a whole.
Discussions on immigrants, borders, the Schengen agreement, civil liberties, Assad, the Islamic State and etc are boiling.
But once things are settling, which proposals and discussions will turn into concrete actions?